CHEN Shi-tong,BAI Jian-bo,LI Meng-jie,et al.Study on Exploitation and Pharmacological Effect on Edible and Pharmaceutical Fungus Polysaccharides[J].Northern Horticulture,2012,36(17):195-198.
食药用菌多糖的药理作用及开发利用研究
- Title:
- Study on Exploitation and Pharmacological Effect on Edible and Pharmaceutical Fungus Polysaccharides
- 文章编号:
- 1001-0009(2012)17-0195-04
- 分类号:
- S 567.3
- 文献标志码:
- A
- 摘要:
- 食药用菌多糖是食药用菌中重要的生物活性成分，现就食药用菌多糖的免疫药理作用、产品开发现状进行综述，提出了目前食药用菌多糖开发、研究中存在的问题及对策。
- Abstract:
- Polysaceharides were the important biologically active components in edible and pharmaceutical fungus.This article presented the current research of its pharmacological effect and exploitation in details，meanwhile，the problems encountered during the research and exploitation of edible and pharmaceutical fungus polysaccharides were also discussed.
参考文献/References:
[1]Solomon P，Wasser.Current findings，future trends，and unsolved problems in studies of medicinal mushrooms[J].Appl Microbiol Biotechnol,2011,89:1323-1332. [2]Chien C M，Cheng J L，Chang W T，et al.Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+NK-cell cytotoxicity in cord blood [J].Bioorg Med Chem,2004(12)：5603-5609. [3]Peng Y F，Zhang L N,Zeng F B，et al.Structure and antitumor activities of the water-soluble polysaccharides from Ganoderma tsugae?mycelium[J].Carbohydr Polym，2005,59:385-392. [4]Weng C J，Yen G C.The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum?on cancer invasion and metastasis[J].Clin Exp Metastasis,2010(27):361-369. [5]Vincent E C Ooi,Liu F.Immunomodulation and anti-cancer activity of polysaccharide-protein complexes[J].Current Medicinal Chemistry，2000(7):715-729. [6]闫训友,王玮,赵英.阿魏侧耳多糖研究进展[J].北方园艺,2007(12):243-245. [7]暴增海,马桂珍.杏鲍菇多糖和营养成分的研究现状[J].北方园艺,2007(6):239-240. [8]张治业.松茸多糖对不同肿瘤细胞系的体外抗肿瘤作用[J].山东医药,2011,51(13):70-71. [9]王嵘,易敏,潘贤英.香菇多糖的体外抗肿瘤活性研究[J].重庆医科大学学报,2011,36(5):572-574. [10]Yu M Y，Xu X Y，Qing Y，et al.Isolation of an anti-tumor polysaccharide from Auricularia polytricha?(jew’s ear) and its effects on macrophage activation [J].Eur Food Res Technol，2009,228:477-485. [11]Song Y N，Hui J，Kou W，et al.Identification of?Inonotus obliquus?and Analysis of Antioxidation and Antitumor Activities of Polysaccharides[J].Curr Microbiol,2008,57:454-462. [12]赵源,刘艳芳,蒋俊,等.不同产地毛头鬼伞子实体多糖特征及其刺激巨噬细胞产生NO的活性[J].食用菌学报,2011,18(3):57-60. [13]贾薇,严淑玲,樊华.姬松茸子实体多糖ABMB3对小鼠免疫功能的影响[J].食用菌学报,2010,17(1):65-68. [14]吴旋,白东清,杨广.灵芝多糖对黄颡鱼免疫细胞活性的影响[J].华北农学报,2011,26(3):195-198. [15]凡军民.毛头鬼伞菌丝体多糖的分离、纯化和化学结构鉴定及生物活性研究[D].南京：南京农业大学,2006. [16]文敏,贾刚,李霞.银耳多糖对生长肥育猪生产性能、免疫功能及肉质的影响[J].动物营养学报,2010,22(6):1644-1649. [17]江益平,马方励,周联,等.香菇多糖对免疫抑制小鼠肠道派氏结T细胞的影响[J].中国药理学通报,2011,27(9):1236-1239. [18]李巧珍,刘朝贵,于海龙,等.猴头菌不同生长发育期粗蛋白、粗多糖含量及水溶性粗多糖体外免疫活性[J].食用菌学报,2011,18(4):73-77. [19]Du X J，Zhang J S，Yang Y，et al.Purification，chemical modification and immunostimulating activity of polysaccharides from Tremella aurantialba?fruit bodies[J].Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)，2010,11(6):437-442. [20]杨曦明,范聪,李慧萍,等.白树花多糖硫酸酯的抗凝血活性研究[J].中国实验诊断学,2010,14(7):1031-1034. [21]王泽平,顾洪雁,伊淑莹.泰山赤灵芝多糖缓解大鼠动脉粥样硬化的分子机制研究[J].中国病理生理杂志,2009,25(12):2310-2313. [22]明建.云南特有食药用菌活性多糖研究[D].重庆：西南大学,2008. [23]Zou X，Guo X，Sun M.pH control strategy in a shaken minibioreactor for polysaccharide production by medicinal mushroom Phellinus linteus?and its anti-hyperlipemia activity[J].Bioprocess Biosyst Eng,2009,32:277-281. [24]Kim D H，Yang B K，Jeong S C,et al.Production of a hypoglycemic，extracellular polysaccharide from the submerged culture of the mushroom，Phellinus linteus[J].Biotechnology Letters,2001,23:513-517. [25]Hu S H，Wang J C，Lien J L，et al.Antihyperglycemic effect of polysaccharide from fermented broth of Pleurotus citrinopileatus [J].Appl Microbiol Biotechnol，2006,70:107-113. [26]Byung R L，Yeom P L，Dae W K，et al.Amelioration of streptozotocin-induced diabetes by Agrocybe chaxingu?polysaccharide[J]．Molecules and Cells，2010(29):349-354. [27]兰瑛,潘志福,张松,等.食药用菌多糖延缓衰老评价体系的研究[J].中药材,2010,33(5):834-837. [28]史亚丽,辛晓林,张昌言,等.黑木耳多糖对生物机体运动能力的影响[J].中国临床康复,2006,10(35):106-108. [29]Li L，Ng T B，Song M,et al.A polysaccharide-peptide complex from abalone mushroom (Pleurotus abalonus) fruiting bodies increases activities and gene expression of antioxidant enzymes and reduces lipid peroxidation in senescence-accelerated mice [J].Appl Microbiol Biotechnol，2007,75:863-869. [30]詹忠根.茶树菇多糖的提取工艺及对活性氧自由基清除作用研究[J].北方园艺,2008(11):184-186. [31]杜志强,王建英.猴头菇多糖生物学功能研究[J].中国酿造,2011(8):124-126. [32]曹晋忠,魏磊,苏红,等.印度块菌粗多糖的提取及抗氧化活性研究[J].山西大学学报，2011,34(1):137-142. [33]Zhao L,Zhao G H,Du M,et al.Effect of selenium on increasing free radical scavenging activities of polysaccharide extracts from a se-enriched mushroom species of the genusGanoderma [J].Eur Food Res Technol,2008,226:499-505. [34]Yuan C F，Huang X N，Cheng L，et al.Evaluation of antioxidant and immune activity of Phellinus ribis?glucan in mice [J].Food Chem,2009,115(2):581-584. [35]郑亚凤,王琦,黄志伟,等.灰树花多糖延缓果蝇衰老作用[J].福建农林大学学报,2010,39(6):625-627. [36]陈艺娟,吴异健,黄一帆,等.猴头菇多糖对呼肠孤病毒感染番鸭组织病变及细胞凋亡的影响[J].中国预防兽医学报,2010,32(1):14-18. [37]李佳佳,鞠玉琳,李杨,等.桦褐孔菌不同提取物抗弓形虫效果的比较[J].河南农业科学,2010(1):119-122. [38]张嫚,胡大坤.香菇多糖对鸡常见病原菌的体外抑菌活性[J].江苏农业科学,2009(5):219-220. [39]Li H P，Lu X X，Zhang S H,et al.Antiinflammatory activity of polysaccharide from Pholiota nameko[J].Biochemistry (Moscow)，2008,73(6):669-675. [40]段县平,马吉飞,李天俊,等.姬松茸多糖对四氯化碳染毒兔肝脏的保护效应[J].天津农学院学报,2003,10(3):23-25. [41]和朝军,李景原,秦广雍,等.灵芝硒多糖的研究进展[J].河南农业科学,2006(3):9-11. [42]李慧芬,李翠妮,徐红星.菌类多糖应用研究进展[J].陕西农业科学,2006(5):77-80. [43]Joseph J，Thozhuthum P P S,Kainoor K J.Polysaccharide protein complex isolated from mushroom Phellinus rimosus?(Berk.) pilat alleviates γ radiationinduced toxicity in Mice[J].Cancer biotherapy and radiopharmaceuticals,2011(26):299-308. [44]李金灿,陆辉,张相日,等.食用菌多糖特性与保健作用研究新进展[J].中国食用菌,2005,24(6):7-11. [45]Khatun S，Islam A，Cakilcioglu U，et al.Research on mushroom as a potential source of Nutraceuticals:a review on Indian perspective[J].American Journal of Experimental Agriculture,2012,2(1):47-73. [46]Lakhanpal T N，Rana M.Medicinal and nutraceutical genetic resources of mushrooms [J].Plant Genetic Resources,2005,3(2):288-303. [47]郝瑞芳.裂褶菌栽培及部分营养效应的研究[D].昆明：云南农业大学,2006. [48]周彪,邓勋,宋小双,等.姬松茸复合多糖保健胶囊加工工艺的研究[J].中国林副特产,2005(5):48-49. [49]刘春卉,谢红,苏槟楠,等.金耳多糖营养饮液的功能学研究[J].食用菌,2001(5):41-42. [50]郝瑞芳,李荣春.灵芝多糖的药理和保健作用及应用前景[J].食用菌学报,2004,11(4):57-62. [51]王方.香菇C91-3菌丝发酵液蛋白(LFP91-3)服液抗肿瘤机制的研究[D].大连：大连医科大学,2010. [52]杜庆.食(药)用真菌多糖的研究进展[J].中国食物与营养,2011,17(5):75-77. [53]陈岗.银耳多糖的功能特性及其应用[J].中国食品添加剂,2011(4):144-148. [54]刘景圣.蜜环菌催眠功能优良菌株筛选和发酵工艺优化研究[D].长春：吉林农业大学,2005. [55]武录平.蜜环菌子实体多糖抗氧化活性的研究及其速溶剂的研制[D].吉林农业大学,2011. [56]郭立忠,宋爱荣,王清吉,等.灰树花多糖胶囊免疫调节作用研究[J].食用菌学报,2004,11(3):34-37. [57]罗长财,陈丽芝.真菌多糖作为饲料剂的功效及应用前景展望[J].饲料博览,2005(2):36-38. [58]Guo F C，Savelkoul H F J，Kwakkel R P，et al.Immunoactive，medicinal properties of mushroom and herb polysaccharides and their potential use in chicken diets[J].World’s Poultry Science Journal，2003(59):427-440.
相似文献/References:
[1]李海平,何玥,闫军,等.响应面法优化超声提取地皮菜多糖工艺研究[J].北方园艺,2013,37(04):138.
[2]谭启明,付瑞敏,李景原,等.响应面法优化微波辅助提取芦荟凝胶多糖工艺[J].北方园艺,2014,38(13):133.
TAN Qi-ming,FU Rui-min,LI Jing-yuan,et al.Optimization of Microwave-assisted Extraction Process of Aloe barbadensis Miller Polysaccharies by Response Surface Method[J].Northern Horticulture,2014,38(17):133.
[3]徐 雷,刘常丽,张 群,等.不同初加工方法对茯苓多糖和三萜类成分的影响[J].北方园艺,2014,38(10):148.
XU Lei,LIU Chang-li,ZHANG Qun,et al.Effect of Different Processing Methods on Polysaccharides and Triterpenes of?Poria [J].Northern Horticulture,2014,38(17):148.
[4]罗 琴,林惠昆,管春平,等.正交实验法优化提取二型鳞毛蕨多糖工艺的研究[J].北方园艺,2013,37(22):146.
LUO Qin,LIN Hui-kun,GUAN Chun-ping,et al.Study on the Optimization of Extraction Technology of Polysaccharide from Dryopteris cochleata Using Orthogonal Experiment[J].Northern Horticulture,2013,37(17):146.
[5]陈玉琴,南海娟,刘坤峰.蕨菜多糖提取及抗氧化特性[J].北方园艺,2014,38(14):128.
CHEN Yu-qin,NAN Hai-juan,LIU Kun-feng.Extraction Technology and Antioxidant Acitvity of Polysaccharide From Pteridium revolutum [J].Northern Horticulture,2014,38(17):128.
[6]魏楠楠,姚 睿,李 阳,等.几种因素对反应器铁皮石斛原球茎生长及有效物质的影响[J].北方园艺,2014,38(14):156.
WEI Nan-nan,YAO Rui,LI Yang,et al.Effect of Several Factors on Accumulation of Biomass and Bioactive Compounds during Bioreactor Culture of Dendrobium candidum PLB[J].Northern Horticulture,2014,38(17):156.
[7]龚庆芳,赵 健,何金祥,等.遮荫对一年生铁皮石斛生长特性、光合特性及多糖含量的影响[J].北方园艺,2014,38(01):148.
GONG Qing-fang,ZHAO Jian,HE Jin-xiang,et al.Effects of Shade Treatment on the Growth and Photosynthetic Characteristics and Polysaccharides Content of Annual Dendrobium officinale [J].Northern Horticulture,2014,38(17):148.
[8]韩凤波,奚广生.不同采收期对轮叶党参有效成分含量的影响[J].北方园艺,2014,38(01):154.
HAN Feng-bo,XI Guang-sheng.Effect of Different Harvest Time on the Effective Component Content of Codonopsis lanceolata [J].Northern Horticulture,2014,38(17):154.
[9]姜少娟.毛竹叶多糖超声提取工艺研究[J].北方园艺,2013,37(13):166.
JIANG Shao-juan.Research on Ultrasonic Wave Extraction of Polysaccharides from Phyllostachys pubescens Leaves[J].Northern Horticulture,2013,37(17):166.
[10]胡月芳.淮山多糖微波法提取及清除羟基自由基的研究[J].北方园艺,2014,38(02):135.
HU Yue-fang.Study on the Microwave Extraction and Hydroxy Radical Scavenging of Yam Polysaccharide[J].Northern Horticulture,2014,38(17):135.
备注/Memo
第一作者简介：陈世通（1986-），男，在读硕士，现主要从事食用菌栽培和育种等研究工作。