[1]张渝,刘玉洁,郭丹妮,等.基于高通量测序的数字基因表达谱技术研究进展[J].北方园艺,2015,39(10):170-176.[doi:10.11937/bfyy.201510043]
　ZHANG Yu,LIU Yu-jie,GUO Dan-ni,et al.Research Progress on Digital Gene Expression Profiling Based on High-throughput Sequencing[J].Northern Horticulture,2015,39(10):170-176.[doi:10.11937/bfyy.201510043]
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基于高通量测序的数字基因表达谱技术研究进展

《北方园艺》[ISSN:1001-0009/CN:23-1247/S] 卷: 第39卷 期数: 2015年10 页码: 170-176 栏目: 出版日期: 2015-05-30
Title:
Research Progress on Digital Gene Expression Profiling Based on High-throughput Sequencing
文章编号:
1001-0009（2015）10-0170-07
作者:
张渝; 刘玉洁; 郭丹妮; 李惠敏; 秦新民
(广西师范大学 生命科学学院，珍稀濒危动植物生态与环境保护教育部重点实验室，广西 桂林 541004）
Author(s):
ZHANG Yu; LIU Yu-jie; GUO Dan-ni; LI Hui-min; QIN Xin-min
(Laboratory of Ecology of Rare and Endangered Species and Environmental Protection，Ministry of Education，College of Life Science，Guangxi Normal University，Guilin,Guangxi 541004)
关键词:
数字基因表达谱; 高通量测序技术; 差异表达基因
Keywords:
digital gene expression profiling; high-throughput sequencing; differentially expressed gene
分类号:
Q 343
DOI:
10.11937/bfyy.201510043
文献标志码:
A
摘要:
数字基因表达谱(digital gene expression profiling，DGE)是一种全面、快速地检测某一物种特定组织在特定状态下基因表达情况的高通量测序技术。通过对基因表达谱的生物信息学搜索、比较和分析，可从中获取基因转录、基因调控、信号转导通路、蛋白质功能等相关信息。该研究主要介绍了数字基因表达谱的原理以及在生物学和医学研究等方面的应用。
Abstract:
Digital gene expression profiling (DGE) is a high-throughput sequencing technologies，which can comprehensively and quickly detect gene expression in a specific tissue under certain conditions of a species.The related information about gene transcription，gene regulation，signal transduction pathway and protein function can be obtained by the search，comparison and analysis on bioinformatics of gene expression profiling.This paper mainly described the principles of digital gene expression profiling and applications in biological，medicine and so on.

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备注/Memo

第一作者简介：张渝（1987-），女，硕士研究生，研究方向为植物基因组学研究。E-mail:1290037351@qq.com.

责任作者：秦新民（1956-），男，教授，现主要从事植物分子生物学等研究工作。E-mail:xmqin@mailbox.gxnu.edu.cn.
基金项目：国家自然科学基金资助项目(31360477)；广西教育厅资助项目(2013YB036)。

更新日期/Last Update: 2015-08-09