|Table of Contents|

Inhibition of Glycosidase by Water Extracts of Rare Edible-medicinal Fungi

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2020年06
Page:
126-133
Research Field:
Publishing date:

Info

Title:
Inhibition of Glycosidase by Water Extracts of Rare Edible-medicinal Fungi
Author(s):
ZHANG Xuesong; LIU Huanying; XIE Chunqin; FAN Junmin; CAO Zheng; MIAO Xue
(College of Tea and Food Science and Technology,Jiangsu Polytechnic College of Agriculture and Forestry,Jurong,Jiangsu 212400)
Keywords:
rare edible-medicinal fungi; water extraction; glycosidase inhibitor
PACS:
-
DOI:
10.11937/bfyy.20192291
Abstract:
Five kinds of water extracts of rare edible-medicinal fungi were used as material,and inhibition rates of glucosidase were detected to compare their inhibitory effects,in order to provide the basis for development of hypoglycemic drugs.The results showed that the water extracts of morchella,phellinus igniarius,ganoderma lucidum,cordyceps cicadae,and cordyceps militaris had different degrees of inhibition on the four glycosidase,and the difference was significant (P<0.05).Among the five water extracts,the extract of phellinus igniarius had the highest inhibition rate (74.8%),slightly lower than the commonly used hypoglycemic drugs acarbose and miglitol,and the extract of cordyceps militaris of the inhibition rate was the lowest (35.9%).The water extract of cordyceps militaris had the highest inhibition ability of α-amylase (9.7%) and was significantly higher than that of miglitol (P<0.05).The water extract of morchella had the lowest inhibition of α-amylase (1.1%).The water extract of morchella showed good inhibition ability to α-glucosidase (15.4%),which was significantly higher than that of acarbose and miglitol (P<0.05),while the extract of ganoderma lucidum had the lowest level of α-glucosidase inhibition (11.2%).Ganoderma lucidum water extract showed higher inhibition ability (10.2%) of maltolase,which was significantly higher than that of miglitol (P<0.05),but same to acarbose.The water extract of Phellinus chinensis had the lowest inhibition rate of maltase (4.6%).The five aqueous extracts still maintained good inhibition of the four glycosidase enzymes at 20-60 ℃ and pH 6-8.

References:

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Last Update: 2020-05-26