|Table of Contents|

Response Surface Methodology for the Optimization of Extraction Technology of Total Flavonoids from Walnut Green Husk(PDF)

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2013年14期
Page:
132-136
Research Field:
Publishing date:

Info

Title:
Response Surface Methodology for the Optimization of Extraction Technology of Total Flavonoids from Walnut Green Husk
Author(s):
LI Hong-juan; FAN Jin-shuan; ZHENG Tao; ZHAO Yun-mei; SU Rui; GAO Zhi-hui
Academy of Forestry,Northwest Agricultural and Forestry University,Yangling,Shaanxi 712100
Keywords:
walnut green husk; flavonoids; ultrasonic assisted extraction; response surface analysis
PACS:
S 664.1
DOI:
-
Abstract:
Taking walnut green husk as materials，six factors including ultrasonic power,ethanol concentration,ultrasonic temperature,ultrasonic time,ratio of solid to liquid and standing time were selected,on the basis of single vfactor experiments,the Box Behnken design(BBD) was used to establish a quadric regression equation for predicting the yield of flavonoids.The results showed that the ethanol volume fraction 62%,ultrasonic temperature 51℃,ultrasonic time 31 min,standing time 6.5 min was the optimitization of extraction technology,which led to estimated and observed values of maximal yield of flavonoids of 1.080% and 1.077%,respectively.It suggested that the optimal extraction conditions were reliable.

References:

[1]全国中草药汇编编写组编.全国中草药汇编上册[M].2版.北京:人民卫生出版社,1996.
[2]江苏新医学院?中药大辞典?下册[M].上海:上海科学技术出版社,1986:1544.
[3]Oliveira I,Sousa A,Ferreira I C F R,et al.Total phenols,antioxidant potentialand antimicrobial activity of walnut(Juglans regia L.)green husks[J].Food and Chemical Toxicology,2008,46:2326-2231.
[4]翟梅枝,王磊,何文君,等.核桃青皮乙醇提取物抑菌活性研究[J].西北植物学报,2009,29(12):2542-2547.[5]Rahimiphnah M,Hamedi M,Mirzapour M.Antioxidant activity and phenolic contents of Persian walnut(Juglans regia L.)green husk extract[J].Afr J Food Sci Technol,2010,1(4):105-111.
[6]王宏虬,缪福俊,李彪,等.核桃青皮提取物对马铃薯蚜虫与瓢虫的杀虫活性[J].江苏农业科学,2012,40(7):112114.
[7]王海香,申照静,杜娟,等.核桃青皮提取物对朱砂叶螨的毒力及相关酶活性的测定[J].林业科学,2008,44(5):70-74.
[8]Carvalho M,Ferreira P J,Men des V S,et al.Human cancer cell antiproliferative and antioxidant activities of  Juglans regia L.[J].Food Chem Toxicol,2010,48:441-447.
[9]Alshatwi A A,Hasan T N,Shafi G,et al.Validation of the antiproliferative fffects of organic extracts from the green husk of  Juglans regia L.on PC3 human prostate cancer cells by assessment of apoptosisrelated genes[J].Evidence Based Complementary and Alternative Medicine,2012.
[10]Liu J X,Di D L,Wei X N,et al.Cytotoxic diarylheptanoids from the pericarps of walnuts(Juglans regia)[J].Planta Med,2008,74:621-627.
[11]翟梅枝,晏婷,王元,等.胡桃属植物青皮和叶的化学成分及其生物活性研究进展[J].西北植物学报,2011,31(10):2133-2138.
[12]李海洋,韩军岐,李志西.核桃青皮有效化学成分提取分离研究综述[J].现代园艺,2012(15):9-11.
[13]Cosmulescu S,Trandafir I,Achim G,et al.Phenolics of green husk in mature walnut fruits[J].Not Bot Hort Agrobot Cluj,2010,38(1):53-59.
[14]Cosmulescu S,Trandafir I,Achim G,et al.Juglone content in leaf and green husk of five walnut(Juglans regia L.)cultivars[J].Not Bot Hort Agrobot Cluj,2011,39(1):237-240.
[15]杨金枝,陈锦屏.核桃资源的综合开发利用[J].食品与药品，2007,9(4):71-73.
[16]赵岩,刘淑萍,吕朝霞.核桃青皮的化学成分与综合利用[J].农产品加工,2008（11）:66-68.
[17]Rong T.Chemistry and biochemistry of dietary polyphenols[J].Nutrients,2010,2:1231-1246.
[18]Yao L H,Jiang Y M,Shi J,et al.Flavonoids in food and their health benefit[J].Plant Food Hum Nutr,2004,59:113-122.
[19]Kelly E H,Anthony R T,Dennis J B.Flavonoid antioxidants：chemistry,metabolism and structureactivity relationships[J].Nutr Biochem,2002,13(10):572-584.
[20]唐浩国.黄酮类化合物研究[M].北京:科学出版社,2009.
[21]慕运动.响应面方法及其在食品工业中的应用[J].郑州工程学院学报,2001,22(3):91-94.
[22]王永菲,王成国.响应面法的理论与应用[J].中央民族大学学报(自然科学版),2005,14(3):236-240.
[23]张守梅,许奇志,张立杰,等.乙醇法提取枇杷叶总黄酮的研究[J].福建果树,2011(2):6-10.
[24]孙墨珑,宋湛谦,方桂珍.核桃楸总黄酮的提取工艺[J].东北林业大学学报,2006,34(1):38-39.

Memo

Memo:
-
Last Update: 2014-08-11