[1]孙悦,任铁强,乔庆东.食品防霉剂富马酸二甲酯的合成[J].北方园艺,2012,36(07):173-174.
SUN Yue,REN Tie-qiang,QIAO Qing-dong.Synthesis Mould Inhibitor of Food Dimethyl Fumarate[J].Northern Horticulture,2012,36(07):173-174.
点击复制
SUN Yue,REN Tie-qiang,QIAO Qing-dong.Synthesis Mould Inhibitor of Food Dimethyl Fumarate[J].Northern Horticulture,2012,36(07):173-174.
食品防霉剂富马酸二甲酯的合成
《北方园艺》[ISSN:1001-0009/CN:23-1247/S]
卷:
第36卷
期数:
2012年07期
页码:
173-174
栏目:
出版日期:
2012-07-16
- Title:
- Synthesis Mould Inhibitor of Food Dimethyl Fumarate
- 文章编号:
- 1001-0009(2012)07-0173-02
- 分类号:
- TS 202.3
- 文献标志码:
- A
- 摘要:
- 以四氯化锡为催化剂，马来酸酐和甲醇为原料，采用“一锅法”催化合成富马酸二甲酯。考察了反应时间、醇酸摩尔比、催化剂的用量对产率的影响，并进行了正交实验设计。结果表明：醇酸摩尔比对产率的影响高度显著，当甲醇与马来酸酐的摩尔比为15∶1，四氯化锡质量分数0.8 g，回流反应时间2.5 h，产率达88.72%。通过熔点测试和红外光谱分析，确定合成产物即是富马酸二甲酯。
- Abstract:
- The dimethyl fumarate was synthesized by one-step method，by using maleic anhydride and methanol as raw material and stannic chloride as catalyst.The effect of the reaction time，the ratio of maleic anhydride to methano and the amount of catalyst on the yield were investigated，the orthogonal design experiment was carried out.The results showed that the ratio of maleic anhydride to methano had obvious influence on the yield.When using the 0.8 g stannic chloride，the molar ratio of methanol to maleic anhydride was 15∶1 and the reaction period was 2.5 h，the product yield was 88.72%.Through testing melting point and infrared analysis，the product was dimethyl fumarate.
参考文献/References:
[1]张兆贵,窦建芝,刘艳蕊.富马酸二甲酯的催化合成[J].化学工程师,2008,10(3):60-61.
[2]谭晓军,王党生.富马酸二甲酯的合成和应用[J].饲料工业,2005,26(8):50-51.
[3]汪锦邦,高学敏,张文宝.新型食品及饲料防腐剂DMF的研究[J].精细化工,1986,3(6):52.
[4]俞善信，丁亮中.富马酸二甲酯合成研究进展[J].现代化工,2000,20(9):21-24.
[5]梅允福.防霉剂富马酸二甲酯的合成、应用和市场前景[J].云南化工,2000,27(4):9-11.
[6]盛书玲,张富娟.新型防霉剂富马酸二甲酯的合成及应用[J].许昌学院学报,2010,29(5):95-96.
[7]翁文,许华丽,李国平.四氯化锡催化乙酸异戊酯的合成[J]．应用化学,2001,18(3):244.
备注/Memo
第一作者简介：孙悦（1981-），女，满族，辽宁盘锦人，硕士，实验师，现主要从事精细化工方面的研究工作。E-mail：sunyue19791980@126.com。
收稿日期：2012-01-10
更新日期/Last Update:
2014-09-05