ZHU Mei-jiao,ZHANG Hai-ling,XU Xiang-ling,et al.Research Advance in the Ubiquitin/26S Proteasome Pathway Regulating Abiotic Stress[J].Northern Horticulture,2015,39(03):188-192.[doi:10.11937/bfyy.201503054]
泛素/26S蛋白酶体途径调节非生物胁迫的研究进展
- Title:
- Research Advance in the Ubiquitin/26S Proteasome Pathway Regulating Abiotic Stress
- Keywords:
- ubiquitin; 26S proteasome; abiotic stress
- 文献标志码:
- A
- 摘要:
- 随着环境的恶化和资源的匮乏，非生物胁迫已成为制约植物生长和发育的重要因素，严重影响农作物的产量和农产品的品质。泛素/26S蛋白酶体途径（ubiquitin/26S proteasome pathway，UPP）通过特异性地降解泛素化修饰的蛋白质，介导了植物生长发育的诸多方面，并在植物应对非生物胁迫过程中起关键的调控作用。该文主要概述了泛素/26S蛋白酶体途径及其调控植物响应非生物胁迫机制的研究进展。
- Abstract:
- With the environmental degradation and resource scarcity，abiotic stress has become an important factor in restricting the plant growth and development，and it has the serious impact on crop yields and the quality of agricultural products.Ubiquitin/26S proteasome pathway (UPP) mediates many aspects of plant growth and development by specifically degrading the ubiquitin-modified proteins，and it plays a pivotal regulatory role in the response to abiotic stress.This paper provided an overview of the ubiquitin/26S proteasome pathway and its research progress on the mechanism of regulating plant responding abiotic stress.
参考文献/References:
[1]Wendy J L,Sophia L S.Abiotic stress tolerance mediated by protein ubiquitination[J］.Journal of Experimental Botany，2012，63(2)：599-616.[2]Goldsterin G,Sxheid M,Hammerling V,et al.Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells[J］.Proceedings of the National Academy of Sciences of the United States of America,1975,72(1):11.[3]Callis J T,Carpenter J,Chin W S J,et al.Structure and evolution of genes encoding polyubiquitin and ubiquitin-like proteins in Arabidopsis thaliana ecotype Columbia[J］.Genetics,1995,139(2)：921-939.[4]刘锴栋,袁长春.泛素/26S蛋白酶体途径及其在植物生长发育中的功能[J］.基因组学与应用生物学,2009,28(6):1219-1228.[5]Hershko A,Ciechanover A.The ubiquitin system[J］.Annual Review Of Biochemistry,1998,67:425-479.[6]Hafield P M,Gosink M M,Carpenter T B,et al.The ubiquitin-activating enzyme (E1) gene family in Arabidopsis thaliana[J］.Plant Journal，1997,11(2):213-226.[7]Attaix D,Combart L,Pouch M N,et al.Cellular control of ubiquitin-proteasome-dependent proteolysis[J］.Indian Journal of Animal Sciences，2002，(E.Suppl.2)：56-63.[8]Xu L,Menard R，Berr A,et al.The E2 ubiquitin-conjugating enzymes，AtUBC1 and AtUBC2，play redundant roles and are involved in activation of FLC expression and repression of flowering in Arabidopsis thaliana[J］.Plant Journal,2009,57:279-288.[9]杨娜,侯巧明,南洁,等.泛素连接酶的结构与功能研究进展[J］.生物化学与生物物理进展，2008,35(1):14-20.[10]Petroski M D,Deshaies R J.Function and regulation of culling-RING ubiquitin ligases[J］.Nat Reviews Molecular Cell Biology,2005,6(1):9-20.[11]Zheng N A.Closer look of the HECTic ubiquitin ligases[J］.Structure,2003,11(1):5-65.[12]Vierstra R D.The ubiquitin-26S proteasome system at the nexus of plant biology[J］.Nat Reviews Molecular Cell Biology,2009(10):385-397.[13]Bates P W,Vierstra R D.UPL1 and 2，two 405 kDa ubiquitin-protein ligases from Arabidopsis thaliana related to the HECT-domain protein family[J］.Plant Journal，1999,20(2):183-195.[14]Book A J,Smalle J,Lee K H,et al.The RPN5 subunit of the 26S proteasome is essential for gametogenesis，sporophyte development，and complex assembly in Arabidopsis[J］.Plant Cell，2009,21(2):460-478.[15]Zhang Y,Feng S，Chen F,et al.Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes[J］.Plant Cell,2008,20(6):1437-1455.[16]Vega-Sánchez M E，Zeng L R,Chen S B.SPIN1，a K homology domain protein negatively regulated and ubiquitinated by the E3 ubiquitin ligase SPL11，is involved in flowering time control in rice[J］.Plant Cell,2008,20(6):1456-1469.[17]Pake B S，Eo H J,Jang I C,et al.Ubiquitination of LHY by SINAT5 regulates flowering time and is inhibited by DET1[J］ Biochemical And Biophysical Research Communications,2010,398(2):242-246.[18]宋素胜,谢道昕.泛素蛋白酶体途径及其对植物生长发育的调控[J］.植物学通报,2006,23(5):564-577.[19]Dreher K,Callis J.Ubiquitin,Hormones and biotic stress in plants[J］.Annals of Botany,2007,99(5):787-822.[20]Santer A,Estelle M.The ubiquitin-proteasome system regulates plant hormone signaling [J］.Plant Journal,2010,61(6):1029-1040.[21]Liu J J,Zhang Y Y,Qin G J,et al.Targeted degradation of the cyclin-dependent kinase inhibitor ICK4/KRP6 by RING-type E3 ligases is essential for mitotic cell cycle progression during Arabidopsis gametogenesis[J］.Plant Cell,2008,20(6):1538-1554.[22]Ren H，Santner A，Pozo J C，et al.Degradation of the cyclin-dependent kinase inhibitor KRP1 is regulated by two different ubiquitin E3 ligases[J］.Plant Journal,2008,53(5):705-716.[23]Lai J B,Chen H,Teng K L,et al.RKP，a RING finger E3 ligase induced by BSCTV C4 protein，affects geminivirus infection by regulation of the plant cell cycle[J］.Plant Journal,2009,57(5):905-917.[24]Henriques R,Jang I C,Chua N H.Regulated proteolysis in light-related signaling pathways[J］.Current Opinion in Plant Biology,2009,12(1):49-56.[25]Hoecker U.Regulated proteolysis in light signaling[J］.Current Opinion In Plant Biology,2005,8(5):469-476.[26]Dong C H,Agarwal M,Zhang Y Y,et al.The negative regulator of plant cold responses,HOS1，is a RING E3 ligase that mediates the ubiquitination and degradation of ICE1[J］.Proceedings of The National Academy of Sciences United States of America，2006,103(21):8281-8286.[27]Lin S S,Martin R,Mongrand S,et al.RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis[J］.Plant Journal,2008,56(4)：550-561.[28]Zeng L R,Qu S H,Bordeos A,et al.Spotted leaf11，a negative regulator of plant cell death and defense，encodes a U-box/armadillo repeat protein endowed with E3 ubiquitin ligase activity[J］.Plant Cell,2004,16(10):2795-2808. [29]Qiao H,Wang H Y,Zhao L,et al.The F-box protein AhSLF-S2 physically interacts with S-RNases that may be inhibited by the ubiquitin/26S proteasome pathway of protein degradation during compatible pollination in Antirrhinum[J］.Plant Cell,2004,16(3):582-595.[30]于晓敏,蓝兴国,李玉花.泛素/26S蛋白酶体途径与显花植物自交不亲和反应[J］.植物学通报，2006,23(2):197-206.[31]Zhang Y J,Zhao Z H,Xue Y B.Roles of proteolysis in plant self-incompatibility[J］.Annual Review of Biology,2009,60:21-42.[32]Craig A,Ewan R,Mesmar J,et al.E3 ubiquitin ligases and plant innate immunity[J］. Journal of Experimental Botany,2009,60(4)：123-1132.[33]Trujillo M,Shirasu K.Ubiquitination in plant immunity[J］.Current Opinion In Plant Biology,2010,13(4):402-408.[34]Zeng L R,Vega-Sánchez M E,Zhu T,et al.Ubiquitination-mediated protein degradation and modification：an emerging theme in plant-microbe in teractions[J］.Cell Research,2006,16(5):413-426.[35]Smalle J,Vierstra R D.The ubiqutitin 26S proteasome proteolytic pathway[J］.Annual Review of Biology,2004,55：555-590.[36]Miller J,Gordon C.The regulation of proteasome degradation by multi-ubiquitin chain binding proteins[J］.FEBS Lett,2005,579(15):3224-3230.[37]Feussner K,Feussner I,Leopold I,et al.Isolation of a cDNA coding for an ubiquitin-conjugating enzyme UBC1 of tomato-the first stress-induced UBC of higher plants[J］.FEBS Lett,1997,409(2):211-215.[38]徐晨曦,姜静,刘甜甜,等.柽柳泛素结合酶基因(E2s)的序列分析及功能验证[J］.东北林业大学学报,2007,35(11):1-4.[39]Zhang Y,Yang C H,Li Y Y,et al.SDIR1 is a RING finger E3 ligase that positively regulates stress-responsive abscisic acid signaling in Arabidopsis[J］.The Plant Cell Online,2007,19(6)：1912-1929.[40]Ryu M Y,Cho S K,Kim W T.The Arabidopsis C3H2C3-Type RING E3 Ubiquitin Ligase AtAIRP1 Is a Positive Regulator of an Abscisic Acid-Dependent Response to Drought Stress[J］.Plant Physiology Preview,2010,154(4):1983-1997. [41]Li H M,Jiang H L,Bu Q Y,et al.The Arabidopsis RING Finger E3 Ligase RHA2b Acts Additively with RHA2a in Regulating Abscisic Acid Signaling and Drought Response1[J］.Plant Physiology Preview,2011,156(2)：550-563. [42]Kim J H,Kim W T.The Arabidopsis RING E3 ubiquitin ligase AtAIRP3/LOG2 participates in positive regulation of high salt and drought stress responses[J］.Plant Physiology Preview,2013(21)：3.[43]Ko J H,Yang S H,Han K H.Upregulation of an Arabidopsis RING-H2 gene，XERICO，confers drought tolerance through increased abscisic acid biosynthesis[J］.Plant Journal,2006，47(3):343-355.[44]Lee H K,Cho S K,Son O,et al.Drought stress-induced Rma1H1，a RING membrane-anchor E3 ubiquitin ligase homolog，regulates aquaporin levels via ubiquitination in transgenic Arabidopsis plants[J］.The Plant Cell Online,2009,21(2):622-641.[45]Cheng M C,Heseh E J,Chen J H,et al.Arabidopsis RGLG2，functioning as a RING E3 ligase，interacts with AtERF53 and negatively regulates the plant drought stress response[J］.Plant Physiology Preview，2012,158(1):363-375.[46]刘方方,姜涛.玉米中RING型E3泛素连接酶基因ZmGW2 的表达分析[J］.玉米科学2013，21(2):47-51.[47]Sakuma Y Maruyama K，Osakabe Y,et al.Functional analysis of an Arabidopsis transcription factor，DREB2A，involved in drought-responsive gene expression[J］.Plant Cell,2006，18(5):1292-1309.[48]Qin F,Sakuma Y,Tran L S P,et al.Arabidopsis DREB2A-interacting proteins functionas RING E3 ligases and negatively regulate plant droughtstress-responsive gene expression[J］.Plant Cell，2008,20(6):1693-1707.[49]Liu Y C,Wu Y R,Huang X H,et al.AtPUB19，a U-Box E3 ubiquitin ligase，negatively regulates abscisic acid and drought responses in Arabidopsis thaliana[J］.Molecular Plant Pathology,2011,4(6):938-946.[50]Seo D H,Ryu M Y，Jammes F，et al.Roles of four Arabidopsis Ubox E3 ubiquitin ligases in negative regulation of ABA-mediated drought stress responses[J］.Plant Physiology Preview,2012，160:556-568.[51]Cho S K,Ryu M Y,Song C,et al.Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress[J］.Plant Cell,2008，20(7):1899-914.[52]Zhang Y，Xu W Y，Li Z H，et al.F-box protein DOR functions as a novel inhibi-tory factor for abscisic acid-induced stomatal closure un-der drought stress in Arabidopsis[J］.Plant Physiology Preview，2008,148(4):2121-2133. [53]Peng M S,Hannam C,Gu H L,et al.A mutation in NLA,which encodes a RING-type ubiquitin ligase，disrupts the adaptability of Arabidopsisto nitrogen limitation[J］.Plant Journal,2007,50(2):320-337.[54]宁约瑟,王国梁,谢旗.泛素连接酶E3介导的植物干旱胁迫反应[J］.植物学报,2011(6):606-616.
备注/Memo
第一作者简介：朱美娇（1990-），女，硕士研究生，研究方向为分子遗传学。E-mail：280737098@qq.com.责任作者：王全伟（1978-），女，博士，副教授，研究方向为分子遗传学。E-mail:wqw125@126.com.基金项目：黑龙江省教育厅面上资助项目（12511154）。