|Table of Contents|

Optimization of Extraction Process and in vitro Antioxidant Activities of Flavonoid From Zizyphus jujuba

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2018年03
Page:
130-138
Research Field:
Publishing date:

Info

Title:
Optimization of Extraction Process and in vitro Antioxidant Activities of Flavonoid From Zizyphus jujuba
Author(s):
ZHANG Hao1; 2; HAO Lihua3; LIU Guiqiao4; YE Jia1; 2; ZHENG Yunpu3; FU Yuwei1
1.School of Life Science and Engineering,Handan University,Handan,Hebei 056005；2.Research Center for Plant Resources Applied Technology in Jinan Mountain at University of Hebei Province，Handan,Hebei 056005；3.School of Water Conservancy and Hydropower,Hebei University of Engineering,Handan,Hebei 056038；4.School of Life Sciences and Food Engineering,Hebei University of Engineering,Handan,Hebei 056038
Keywords:
orthogonal array design; flavonoids; antioxidant activity; Zizyphus jujuba; DPPH?
PACS:
-
DOI:
10.11937/bfyy.20172782
Abstract:
With single factor and orthogonal array design L9 （34) experiments,this study investigated the optimal process parameters for extracting flavonoids from different tissues of Zizyphus jujuba,which was sampled from the Taihang Mountains locates at south of Hebei Province,China.Meanwhile,the scavenging effects of flavonoids on DPPH? were also examined.The results showed that the extraction yield of flavonoids was 10.13% with the optimal parameters that the ethanol concentration,solid-liquid ratio,extraction time,and extraction temperature were 65%,1∶20 g?mL-1,2.5 hours,and 60 ℃ for stems；the extraction yield of flavonoids was 14.15% with the optimal parameters that the ethanol concentration,solid-liquid ratio,extraction time,and extraction temperature were 65%,1∶10 g?mL-1,2.0 hours,and 60 ℃ for roots；the extraction yield of flavonoids was 18.98% with the optimal parameters that the ethanol concentration,solid-to-liquid ratio,extraction time,and extraction temperature were 65%,1∶25 g?mL-1,3.0 hours,and 65 ℃ for leaves；the extractions from the stems,roots,and leaves of Zizyphus jujuba characterized by high antioxidant ability for scavenging the DPPH? with the scavenging ability from high to low was leaves>roots>stems.

References:

[1]延玺,刘会青,邹永青,等.黄酮类化合物生理活性及合成研究进展[J].有机化学,2008（9):1534-1544.

[2]许晖,孙兰萍,张斌,等.花生壳黄酮类化合物的研究进展[J].农产品加工,2008（3):11-15.
[3]董晓宁,赵海福,赵强,等.中草药提取物抗氧化作用及其机理研究进展[J].中兽医医药杂志,2014（1):25-29.
[4]陈梅霞,苏洁,张玥莉,等.银杏叶提取物与银杏黄酮对高脂血症大鼠血脂水平影响的比较研究[J].中国新药杂志,2014（7):833-838.
[5]李洪玉,孙静芸.竹叶化学成分研究[J].中药材,2003,26（8):562-563.
[6]罗金岳,陈小燕.从箬竹叶中提取茶多酚的研究[J].林产化工通讯,2003,37（6):15-19.
[7]张英,吴晓琴,俞卓裕.竹叶黄酮和内酯的季节性变化规律研究[J].林业化学与工业,2002（22):65-69.
[8]周荣汉.药用植物化学分类学[M].上海:科学技术出版社,1988:123-141.
[9]黄文,王益.竹叶提取物抑菌特性的研究[J].林产化学与工业,2002（22):68-70.
[10]庞战军,周玖,陈瑗.自由基医学研究方法[M].北京:人民卫生出版社,2000.
[11]CAYUELA M M.Oxygen free radicals and human disease[J].Biochimie,1995,77:147-161.
[12]MARNETT L J.Oxygen radicals,lipid peroxidation and DNA damage[J].Toxicology,2002,181:219-222.
[13]中国植物志编辑委员会.中国植物志（第1卷)[M].北京:科学出版社,1959.
[14]石丽霞,张振家.复方大枣口服液对小鼠免疫机能的影响[J].吉林医药学院学报,2005,26（1):41-42.
[15]苏新医学院.中药人辞典[M].上海:上海人民出版社,上册:397,下册:15-64.
[16]史琪荣,周耘,周萍,等.中药酸枣仁的研究概况[J].药学实践杂志,2004,22（2):94-96.
[17]王晓荣,魏朔男,李薇薇.沙枣叶化学成分的HPLC分析[J].陕西农业科学,2013,41（1):66-68.
[18]李全国,楚杰,王君高,等.乐陵枣叶中总黄酮提取工艺研究[J].中国食物与营养,2013,19（7):51-54.
[19]孙庆雷,王晓,刘建华,等.黄酮类物质抗氧化反应性的构效关系[J].食品科学,2005,26（4):69-73.
[20]李卫,宁正祥.黄酮类化合物的分子修饰[J].食品科学,2005,26（8):505-507.
[21]张德权,台建祥,付勤.生物类黄酮的研究及应用概况[J].食品与发酵工业,1999,25（6):52-57.
[22]焦艳,闻杰,于晓红,等.膜荚黄芪茎叶总黄酮对小鼠细胞免疫功能的影响[J].中国中西医结合杂志,1999,19（6):356-358.
[23]杨学山,祝霞,李颖,等.正交实验优化葡萄酒酵母甘露聚糖提取工艺及其体外抗氧化作用[J].食品科学,2015,36（18):69-74.
[24]王勇.酸枣适应干旱的生理特征和氧化还原特征物质研究[D].北京:中国科学院大学,2015.
[25]董芳.酸枣叶中黄酮类物质的抗旱生理功能研究[D].杨凌:西北农林科技大学,2009.

Memo

Memo:
-
Last Update: 2018-02-09