|Table of Contents|

Response Surface Optimization of Ultrasound-assisted Ethanol Extraction of Shikimic Acid From Ginkgo biloba Leaves

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2024年19
Page:
99-107
Research Field:
Publishing date:

Info

Title:
Response Surface Optimization of Ultrasound-assisted Ethanol Extraction of Shikimic Acid From Ginkgo biloba Leaves
Author(s):
YU Wanwen1; YANG Sen1; ZHAO Dan1; WU Xiangqian2
(1.Co-innovation Center for the Sustainable Forestry in Southern China，Nanjing Forestry University，Nanjing，Jiangsu 210037；2.School of Landscape Architecture，Jiangsu Vocational College of Agriculture and Forestry，Jurong，Jiangsu 212400)
Keywords:
Ginkgo biloba; shikimic acid; ultrasonic-assisted extraction; process optimization
PACS:
S 792.95
DOI:
10.11937/bfyy.20241071
Abstract:
Shikimic acid was extracted from dried leaves of Ginkgo biloba L.by ultrasonic-assisted 70% ethanol.The extraction process was optimized by single factor experiment and response surface experiment.The effects of material-liquid ratio，extraction temperature，extraction time and extraction times on the extraction rate of shikimic acid were studied，and the optimum extraction process was optimized，in order to provide reference for the extraction of shikimic acid from Ginkgo biloba leaves.The results showed that the optimum technological conditions were as follows,material-liquid ratio 1∶8 g·mL-1，extraction temperature 66 ℃，extraction time 65 minutes (once for each extraction) and extraction times twice.Under these conditions，the extraction yield of shikimic acid from Ginkgo biloba leaves was 1.805%，which was close to the theoretical yield (1.883%).

References:

［1］刘永友,廖晓峰.莽草酸的研究进展［J］.化工时刊,2007,21(3):54-57.［2］何邵平,禹琪芳,段杰林,等.莽草酸的制备及其生物学功能研究进展［J］.饲料博览,2014(10):32-36.［3］秦超逸,朱国琴,王军,等.银杏中莽草酸的测定方法及其应用研究进展［J］.中国医药工业杂志,2022,53(2):184-191.［4］王祖磊.莽草酸新资源及其分离纯化方法的研究［D］.杭州:浙江大学,2010.［5］郁万文,赵丹,刘国华.超声辅助提取银杏叶莽草酸工艺优化［J］.应用化工,2023,52(6):1660-1664.［6］曹春月,陈前袆,王黔阳,等.正交设计优化银杏叶中4种活性成分综合提取工艺［J］.化学与粘合,2020,42(2):84-87.［7］彭善贵,许莉,曾桢,等.HPLC法测定八角茴香中莽草酸和反式茴香脑含量［J］.中国药师,2018,21(9):1665-1666,1674.［8］张敏,米佳宁,杨晓岚,等.八角茴香水溶性成分HPLC指纹图谱及莽草酸的定量研究［J］.上海中医药杂志,2011,45(12):91-95.［9］刘鹏,付艺萱,张旭超,等.5种采集条件下银杏落叶中莽草酸的含量［J］.应用与环境生物学报,2022,28(1):104-110.［10］林海禄,彭雪娇,罗明标,等.微波辅助提取八角茴香中莽草酸的工艺研究［J］.食品工业科技,2007,28(3):137-138,142.［11］郑曌钰,王浩宇,肖亚楠,等.响应面法优化菊花类黄酮微波辅助提取工艺［J］.北方园艺,2023(22):84-93.［12］任倩倩,高朋,马致静,等.响应面法优化超声辅助提取北柴胡黄酮工艺及抗氧化活性［J］.北方园艺,2023(5):93-100.［13］林海禄,彭雪娇,罗明标,等.八角茴香中莽草酸超声提取工艺研究［J］.食品科技,2007,32(4):76-78.［14］吴雅露,陈琪,陈梦涛,等.响应面法优化藜麦种子黄酮的超声波辅助提取工艺［J］.食品研究与开发,2019,40(21):100-106.［15］ZELAYA I A,ANDERSON J A H,OWEN M D K,et al.Evaluation of spectrophotometric and HPLC methods for shikimic acid determination in plants:models in glyphosate-resistant and-susceptible crops［J］.Journal of Agricultural and Food Chemistry,2011,59(6):2202-2212.［16］伦琦,乔镜澄,杨江南,等.响应面分析法优化银杏叶黄酮类化合物的提取工艺［J］.食品安全导刊,2023(12):137-140,144.［17］曾思漫,崔珏.银杏叶黄酮的闪式提取工艺优化及抗氧化活性分析［J］.农产品加工,2021(17):36-38,42.［18］于德涵,黎莉,苏适,等.响应面优化银杏叶中总黄酮的超声提取工艺研究［J］.广州化工,2020,48(8):64-67.［19］申伟培,黄伟贞,黄振光.正交设计优化银杏叶中黄酮和萜内酯类成分的提取工艺［J］.中药材,2016,39(12):2833-2835.［20］朱兴一,谢捷,忙怡丽,等.微波辅助提取银杏叶萜类内酯的工艺研究［J］.高校化学工程学报,2009,23(6):1080-1083.

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Last Update: 2024-10-21