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Quality Evaluation and Quality Equivalence of Three Gentianaceous Medicinal Plants of Bai Nationality(PDF)

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2016年18
Page:
165-170
Research Field:
Publishing date:

Info

Title:
Quality Evaluation and Quality Equivalence of Three Gentianaceous Medicinal Plants of Bai Nationality
Author(s):
HAN Duo1; ZHAO Zhilian2; LIU Weihong3; LI Yuehua4; LI Haifeng1
(1.College of Pharmacy and Chemistry，Dali University，Dali,Yunnan 671000;2.Dali Vocational and Technical College of Agriculture and Forestry，Dali,Yunnan 671003;3.Library of Dali University，Dali,Yunnan 671000;4.Dali Analysis and Testing Center of Yunnan Province，Dali,Yunnan 671000)
Keywords:
Gentiana rigescens Franch.; Gentiana cephalantha Franch.; Gentiana delavayi Franch.; quality evaluation; content determination
PACS:
-
DOI:
10.11937/bfyy.201618041
Abstract:
The contents of gentiopicroside，swertiamarin，sweroside and amarogentin in the roots of Gentiana rigescens Franch.，Gentiana cephalantha Franch.and Gentiana delavayi Franch.were determined by HPLC，the quality and quality equivalence were evaluated by one-way ANOVA，cluster analysis and chromatographic analysis.The results showed that Gentiana delavayi Franch.had significant difference(P<001)with Gentiana rigescens Franch.and Gentiana cephalantha Franch.in the contents of gentiopicroside，swertiamarin，sweroside and amarogentin in the roots，there was no significant difference between Gentiana rigescens Franch.and Gentiana cephalantha Franch.，and their contents of gentiopicroside in the roots were more than five times the national standard，but the contents of gentiopicroside was not detected in the roots of Gentiana delavayi Franch.The similarities of the characteristic peaks of Gentiana rigescens Franch.and Gentiana cephalantha Franch.in HPLC fingerprints were 0997，while Gentiana delavayi Franch.was just 0015.The contents and total contents of gentiopicroside，swertiamarin，sweroside and amarogentin of Gentiana rigescens Franch.，Gentiana cephalantha Franch.and Gentiana delavayi Franch.were similar as shown by cluster analysis，Gentiana rigescens Franch.and Gentiana cephalantha Franch.were cluster into one group，while Gentiana delavayi Franch.was a separate category.Gentiana cephalantha Franch.could replace Gentiana rigescens Franch.into medicine，but it needed to have further studies of pharmacological，toxicological experiments，while Gentiana delavayi Franch.not.

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Last Update: 2016-11-01