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Study on Optimization of the Extraction of Artemisinin(PDF)

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2014年11期
Page:
122-125
Research Field:
Publishing date:

Info

Title:
Study on Optimization of the Extraction of Artemisinin
Author(s):
ZHANG Ying1; 2
1.College of Biological and Chemistry Engineering,Panzhihua University,Panzhihua,Sichuan 617000;
2.Key Laboratory of Dry-hot Valley Characteristic Bio-Resources Development at University of Sichuan Province,Panzhihua,Sichuan 617000
Keywords:
artemisinin; orthogonal experiments; extraction rate; optimal process
PACS:
R 282. 71
DOI:
-
Abstract:
Taking dry leaves of Artemisia annua L. as material and extracted yield of artemisinin as investigate indicator,artemisinin was extracted form dry leaves of Artemisia annua L.by using organic solvent methods.Material liquid ratio,extracting temperature and time were selected as experimental factors,orthogonal experiment was carried out on the basis of single factor experiments,in order to study the optimal extraction conditions of artemisinin.The results showed that the optimal conditions for artemisinin extraction were material-liquid ratio 1∶20 g/mL,extraction temperature 50℃ and extraction time 2.5 h,extracting amount of artemisinin was up to 5.27 mg/g.

References:

[1]   孔建强,王伟,程克棣,等.青蒿素的合成生物学研究进展[J].药学学报,2013,48(2):193-205.
[2]   王满元.青蒿素类药物的发展历史[J].自然杂志,2012,34(1):44-47.
[3]   卢义钦.青蒿素的发现与研究进展[J].生命科学研究,2012,16(3):260-265.
[4]   梅林,石开云.青蒿素国内研究进展[J].激光杂志,2008,29(2):95-96. 
[5]   凌立新,张国芬,姚晨.青蒿素提取工艺研究[J].亚太传统医药,2009,5(2):37-38.
[6]   张犇,王剑文.青蒿素检测方法的研究近况[J].抗感染药学,2008,5(4):201-204.
[7]   阚毓铭,黄泰康.中药化学实验操作技术[M].北京:中国医药科技出版社,1998.
[8]   梁晓媛,李隆云,白志川.青蒿中青蒿素提取工艺研究进展[J].重庆理工大学学报(自然科学),2013,27(2):32-38.
[9]   周毅峰,石开明,艾训儒,等.快速溶剂萃取法提取青蒿素条件研究[J].中药材,2008,31(2):296-298.
[10] 张玲,杜小英,姜锦花.蒿素提取分离工艺研究[J].现代中药研究与实践,2005,19(6):57-58.

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Last Update: 2014-08-05