|Table of Contents|

Research Advances in Chemical Constitution and Pharmacological Activities of Morus(PDF)

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2014年21期
Page:
202-205
Research Field:
Publishing date:

Info

Title:
Research Advances in Chemical Constitution and Pharmacological Activities of Morus
Author(s):
NIU Tian-yuLIU Hong-zhangLIU Shu-ying
College of Life Science,Jilin Agricultural University,Changchun,Jilin 130118
Keywords:
Moruschemical constitutioninsulindiabetes
PACS:
S 567.1+9
DOI:
-
Abstract:
Summarized the developing of classification onMorus from morphology to molecular biology,in recent years,the research on chemical constitution,structure and pharmacological activities ofMorus was elaborated.Hypoglycemic mechanism of Morus was elaborated from two impacts,which were promote insulin activity and control blood sugar levels.

References:

[1]陈仁芳.桑属系统学研究[D].武汉:华中农业大学,2010:68-71.
[2]杨文宇,万德光.中国桑树分类及桑类中药原植物考辨(1)[J].时珍国医国药,2008,19(11):324-327.
[3]杨光伟.中国桑属(Morus L.)植物遗传结构及系统发育分析[D].重庆:西南农业大学,2003:47-51.
[4]Kalpana D,Choi S H,Choi T Ki,et al.Assessment of genetic diversity among varieties of mulberry using rapd and issr fingerprinting[J].Scientia Horticulturae,2012,134:79-87.
[5]Wang Y H,Xiang L M,Wang C H,et al.Antidiabetic and antioxidant effects andphytochemicals of mulberry fruit(Morus alba L.)polyphenol enhanced extract[J].PloS One,2013,8(7):e71144.
[6]Wanyo P,Siriamornpun S,Meeso N.Improvement of quality and antioxidant properties of dried mulberry leaves with combined far-infrared radiation and air convection in thai tea process[J].Food and Bioproducts Processing,2011,89(1):22-30.
[7]Bae S H,Suh H J.Antioxidant activities of five different mulberry cultivars in Korea[J].LWT-Food Science and Technology,2007,40(6):955-962.
[8]胡金奎.桑葚花色苷的分离制备,结构分析及其体外活性[D].无锡:江南大学,2013:35-46.
[9]Du Q,Zheng J,Xu Y.Composition of anthocyanins in mulberry and their antioxidant activity[J].Journal of Food Composition and Analysis,2008,21(5):390-395.
[10]刘利.桑叶次生代谢产物研究[D].北京:中国农业科学院,2005:27-63.
[11]佟亚楠.桑枝化学成分的研究[D].长春:吉林大学,2013:13-26.
[12]Zhang Y L,Luo J G,Wan C X,et al.Geranylated 2-arylbenzofurans from Morus alba var. Tatarica and their alpha-glucosidase and protein tyrosine phosphatase 1b inhibitory activities[J].Fitoterapia,2014,92:116-126.
[13]Lin C Y,Lay H L.Characteristics of fruit growth,component analysis and antioxidant activity of mulberry(Morus spp.)[J].Scientia Horticulturae,2013,162:285-292.
[14]Yu Y S,Xu Y J,Wu J J,et al.Effect of ultra-high pressure homogenisation processing on phenolic compounds,antioxidant capacity and anti-glucosidase of mulberry juice[J].Food Chemistry,2014,153:114-120.
[15]陈城城.桑叶化学成分研究[D].齐齐哈尔:齐齐哈尔大学,2012:25-37.
[16]Ercisli S,Orhan E.Some physico-chemical characteristics of black mulberry(Morus nigra L.)genotypes from northeast anatolia region of turkey[J].Scientia Horticulturae,2008,116(1):41-46.
[17]Sun F,Shen L,Ma Z J.Screening for ligands of human aromatase from mulberry(Morus alba L.)leaf byusing high-performance liquid chromatography/tandem mass spectrometry[J].Food Chemistry,2011,126(3):1337-1343.
[18]Jeszka-Skowron M,Flaczyk E,Jeszka J,et al.Mulberry leaf extract intake reduces hyperglycaemia in streptozotocin(stz)-induced diabetic rats fed high-fat diet[J].Journal of Functional Foods,2014,8:9-17.
[19]Li Y G,Ji D F,Zhong S,et al.Hybrid of 1-deoxynojirimycin and polysaccharide from mulberry leaves treat diabetes mellitus by activating pdx-1/insulin-1 signaling pathway and regulating the expression of glucokinase,phosphoenolpyruvate carboxykinase and glucose-6-phosphatase in alloxan-induced diabetic mice[J].Journal of Ethnopharmacology,2011,134(3):961-970.
[20]Zhang M,Chen M,Zhang H Q,et al.In vivo hypoglycemic effects of phenolics from the root bark ofMorus alba[J].Fitoterapia,2009,80(8):475-477.
[21]Hansawasdi C,Kawabata J.Alpha-glucosidase inhibitory effect of mulberry(Morus alba)leaves on Caco-2[J].Fitoterapia,2006,77(7-8):568-573.
[22]He H,Lu Y H.Comparison of inhibitory activities and mechanisms of five mulberry plant bioactive components against alpha-glucosidase[J].Journal of Agricultural and Food Chemistry,2013,61(34):8110-8119.
[23]刘先明,李琳,王元净,等.桑枝皮提取物对急性高血脂症小鼠血脂水平的影响[J].蚕业科学,2011,37(4):771-774.
[24]Naowaboot J,Chung C H,Pannangpetch P,et al.Mulberry leaf extract increases adiponectin in murine 3T3-L1 adipocytes[J].Nutrition Research,2012,32(1):39-44.
[25]Chang J J,Hsu M J,Huang H P,et al.Mulberry anthocyanins inhibit oleic acid induced lipid accumulation by reduction of lipogenesis and promotion of hepatic lipid clearance[J].Journal of Agricultural and Food Chemistry,2013,61(25):6069-6076.
[26]Hsu L S,Ho H H,Lin M C,et al.Mulberry water extracts(MWEs)ameliorated carbon tetrachloride-induced liver damages in rat[J].Food Chem Toxicol,2012,50(9):3086-3093.
[27]Shih P H,Chan Y C,Liao J W,et al.Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry(Morus atropurpurea L.)on senescence-accelerated mice and prevention of alzheimer’s disease[J].Nutrition Biochemistry,2010,21(7):598-605.
[28]Katsube T,Imawaka N,Kawano Y,et al.Antioxidant flavonol glycosides in mulberry(Morus alba L.)leaves isolated based on LDL antioxidant activity[J].Food Chemistry,2006,97(1):25-31.
[29]Chang L W,Juang L J,Wang B S,et al.Antioxidant and antityrosinase activity of mulberry(Morus alba L.)twigs and root bark[J].Food Chemistry Toxicol,2011,49(4):785-790.
[30]Park E,Lee S M,Lee J E,et al.Anti-inflammatory activity of mulberry leaf extract through inhibition of NF-κB[J].Journal of Functional Foods,2013,5(1):178-186.
[31]Liu C J,Lin J Y.Anti-inflammatory effects of phenolic extracts from strawberry and mulberry fruits on cytokine secretion profiles using mouse primary splenocytes and peritoneal macrophages[J].International Immunopharmacol,2013,16(2):165-170.
[32]Liu C J,Lin J Y.Protective effects of strawberry and mulberry fruit polysaccharides on inflammation and apoptosis in murine primary splenocytes[J].Journal of Food and Drug Analysis,2014,2(10):1-10.
[33]Lim H J,Jin H G,Woo E R,et al.The root barks of Morusalba and the flavonoid constituents inhibit airway inflammation[J].Journal of Ethnopharmacology,2013,149(1):169-175.
[34]Deepa M,Sureshkumar T,Satheeshkumar P K,et al.Purified mulberry leaf lectin(MLL)induces apoptosis and cell cycle arrest in human breast cancer and colon cancer cells[J] Chemistry Biol Interact,2012,200(1):38-44.
[35]Huang H P,Chang Y C,Wu C H,et al.Anthocyanin-rich mulberry extract inhibit the gastric cancer cell growth in vitro and xenograft mice by inducing signals of p38/p53 and c-jun[J].Food Chemistry,2011,129(4):1703-1709.
[36]吕欢,闻燕,王俊,等.桑椹汁对结肠癌细胞株Sw620增殖和凋亡的影响[J].蚕业科学,2013,39(2):394-395.
[37]马斌.桑树枝条韧皮部桑根皮素的制备及其对小鼠h-(22)细胞株移植性肿瘤的抑制作用[D].苏州:苏州大学,2013:41-54.
[38]Zhang M,Wang R R,Chen M.et al.A new flavanone glycoside with anti-proliferation activity from the root bark of Morus alba,Chinese[J].Journal of Natural Medicines,2009,7(2):105-107.
[39]Jiang D Q,Guo Y,Xu D H,et al.Antioxidant and anti-fatigue effects of anthocyanins of mulberry juice purification(MJP)and mulberry marc purification(MMP)from different varieties mulberry fruit in China[J].Food Chem Toxicol,2013,59:1-7.
[40]韩蕾,黄卫,于滢,等.桑枝对小鼠脑缺血再灌注损伤的保护作用[J].中华中医药学刊,2012,30(9):1945-1947. [41]Park K M,You J S,Lee H Y,et al.Kuwanon G:An antibacterial agent from the root bark ofMorus alba against oral pathogens [J].Journal of Ethnopharmacology,2003,84(2-3):181-185.
[42]Du J,He Z D,Jiang R W,et al.Antiviral flavonoids from the root bark of Morus alba L.[J].Phytochemistry,2003,62(8):1235-1238.
[43]Dat N T,Binh P T,Quynh Le T P,et al.Cytotoxic prenylated flavonoids from Morus alba[J].Fitoterapia,2010,81(8):1224-1227.
[44]方飞.桑叶有效部位改善Hepg2胰岛素抵抗及其机制的研究[D].广州:华南理工大学,2012:8-12.
[45]窦梅,马爱国.胰岛素抵抗主要原因及机制的研究进展[J].国外医学卫生学分册,2009,36(3):174-179.
[46]Honka M J,Vanttinen M,Iozzo P,et al.The Pro 12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2diabetes mellitus[J].Metabolism,2009,58(4):541-546.
[47]王江东.细胞因子IL-10及Tnf-α基因多态性及其血清水平与2型糖尿病发病机理的研究[D].石家庄:河北医科大学,2010:62-65.

Memo

Memo:
-
Last Update: 2014-12-01