Study on the Optimization of Ganoderic Acids from Ganoderma lucidum After Fermentation by Supercritical Fluid Extraction Method(PDF)

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Title:: Study on the Optimization of Ganoderic Acids from Ganoderma lucidum After Fermentation by Supercritical Fluid Extraction Method

Abstract:: Taking Ganoderma lucidum as material,the optimization of Ganoderic acids from Ganoderma lucidum after fermentation were studied by supercritical fluid extraction methed.On the basis of single factor experiment，L₉(3⁴)orthogonal was used to optimize the extraction conditions.The results showed that the extraction pressure was significant factors，while extraction temperature and CO₂ velocity had no significant effect on the yield of ganoderic acids.The optimization conditions was as follows：30 MPa extraction pressure，extraction temperature 30℃，CO₂ flow 1.6 L/min，the content of Ganoderic acids reached (23.93±1.85) mg/g under the conditions,so the optimization conditions was suitable for the Supercritical fluid extraction of Ganoderic acids from Ganoderma Lucidum after fermentation.

[1]刘媛，丁重阳，章克昌，等.10种中药对灵芝液体发酵的影响[J]．食品与生物技术学报，2008，27(2):123-126.

[2]王玉红，丁重阳，章克昌．苦荞对灵芝发酵生产灵芝酸的影响[J]．食品与发酵工业，2004，29(9):95-98.

[3]王晓玲，刘昭廷．灵芝菌丝体中灵芝酸的体外抑菌作用[J]．食品科技，2008(10):184-186.

[4]张景伟．超临界CO₂萃取山茱萸中有效成分的工艺研究[D]．郑州：郑州大学，2005.

[5]孙金旭．灵芝紫外诱变育种研究[J]．中国酿造，2009（8）:63-66.

[6]鄢嫣，聂少平，陈奕．灵芝氯仿提取物的HPLC指纹图谱的研究[J]．食品与生物技术学报，2009，28(5):589-593.

[7]凌庆枝，王林，魏兆军，等．pH值控制灵芝发酵产生灵芝酸的研究[J]．中国酿造，2009，204(3):117-120.

Last Update: 2014-08-27