With tomato variety of non resistance “Red one” as the test material，the field efficacy of new pure Chinese medicne biological agents-TY virus Ⅱ which developed by Weifang Aofeng Crop Virus Control Co.，Ltd on tomato TY virus were studied.The results showed that 7 days after using TY virus Ⅱ in first drug treatment，the control effect of pure Chinese medicine 700 times，500 times，300 times were 59.58%，64.75%，68.86%，respectively.7 days after using TY virus Ⅱ in second drug treatment，the control effect were 68.63%，76.37%，82.88%，respectively.Among which the control effect of 300 times liquor was the best compared with viral A control and water.It also had apparent stilulative effect on tomato growth，and could be widely used in the production.