|Table of Contents|

Optimization of Extraction Technology for Total Flavonoids from Eupatorium odoratum L.by Response Surface Methodology(PDF)

《北方园艺》[ISSN:1001-0009/CN:23-1247/S]

Issue:
2012年15期
Page:
78-82
Research Field:
Publishing date:

Info

Title:
Optimization of Extraction Technology for Total Flavonoids from Eupatorium odoratum L.by Response Surface Methodology
Author(s):
WANG Gui-rong; ZHANG Yan-di; ZHANG Lian-xue
College of Chinese Medicinal Materials，Jilin Agriculture University，Changchun，Jilin 130118
Keywords:
Eupatorium odoratum L.; flavonoids; response surface methodology
PACS:
Q 946
DOI:
-
Abstract:
Response surface methodology (RSM) was applied to optimize extraction process of total flavonoids from Eupatorium odoratum L.Based on single experiments，extraction temperature，extraction time，ratio of liquid to solid and ethanol concentration were selected for Box-Behnken central composite designing．RSM was employed to study the effect of these factors on the yield of total flavonoids.The results showed that canonical analysis of surface responses revealed the stationary surface was a maximum.The coefficient of determination was 0.9722.The optimal process conditions were extraction temperature 80℃，extraction time 4.5 hours，ratio of liquid to solid 1∶41 and ethanol concentration 51%.Under these optimized conditions，the extraction yield of total flavonoids was up to 7.162%.

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Last Update: 2014-08-28